Impact of Topical Steroid Nasal Irrigation Adherence on Chronic Rhinosinusitis and Allergic Rhinitis Patient…

Cohort studyLaryngoscope investigative otolaryngology· Aug 2026

Impact of Topical Steroid Nasal Irrigation Adherence on Chronic Rhinosinusitis and Allergic Rhinitis Patient Outcomes.

Clifford Jiajun He, Omer Baker, Olivia LaMonte … Carol H Yan

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Allergy & ImmunologyCohort studyTreatmentQ1IF 1.9

Greater budesonide nasal rinse adherence associated with lower sinus discomfort scores.

Impact of Topical Steroid Nasal Irrigation Adherence on Chronic Rhinosinusitis and Allergic Rhinitis Patient Outcomes.

Clifford Jiajun He … Carol H Yan

Laryngoscope investigative otolaryngology · Aug 2026 · Q1 in Otorhinolaryngology

Background

High volume steroid nasal rinses are often prescribed for chronic rhinosinusitis and allergic rhinitis.

Purpose

This study aims to investigate the effect of topical steroid nasal rinse adherence on patient outcomes.

Methods

This prospective longitudinal study recruited 97 patients with chronic rhinosinusitis or allergic rhinitis.

n = 97 patients

Results

higher adherence to nasal rinses lowered sinus discomfort scores

47.5%

Overall median adheren

55.6%

Recent surgery (<3 mon

51.6%

SNOT-22 ≥ 20

More results

Median adherence was overall 47.5%, higher in patients with recent sinus surgery (< 3 months: 55.6%) and higher baseline symptom severity (SNOT-22 ≥ 20: 51.6%), with correspondingly larger improvements in clinical outcomes.

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Conclusion · 1 of 2

Objective adherence to budesonide sinus irrigation significantly associates with improved patient-reported outcomes, with the strongest benefit seen in patients with higher baseline symptoms and in the early postoperative period.

Conclusion · 2 of 2

Targeting adherence interventions may yield clinically meaningful improvements in sinonasal quality of life. LEVEL OF EVIDENCE: 2.

Impact of Topical Steroid Nasal Irrigation Adherence on Chronic Rhinosinusitis and Allergic Rhinitis Patient Outcomes.

Impact of Topical Steroid Nasal Irrigation Adherence on Chronic Rhinosinusitis and Allergic Rhinitis Patient Outcomes.

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