Structural brain injury on magnetic resonance imaging in heart failure and identifying patients at high-risk.

In those without large infarcts, most showed WMHs (93.9%) and cerebral atrophy (72.8%).

Smoking (OR: 5.069, P=0.004), diabetes (OR: 3.140, P=0.028), and serum N-terminal pro-brain natriuretic peptide (NT-proBNP) ≥900 pg/mL (OR: 3.472, P=0.023) were associated with large brain infarcts.

Age (OR: 1.075, P=0.002), hypertension (OR: 3.075, P=0.019), higher plasma fibrinogen level (OR: 2.039, P=0.012), and increased serum high-density lipoprotein cholesterol (HDL-C; OR: 7.100, P=0.041) predicted higher white matter hyperintensities Scheltens score.