Comparative study of transbronchial cryobiopsy and transbronchial biopsy for diagnostic yield in peripheral pulmonary lesions.
Transbronchial cryobiopsy yielded a higher diagnostic rate than forceps biopsy for peripheral lung lesions.
Comparative study of transbronchial cryobiopsy and transbronchial biopsy for diagnostic yield in peripheral pulmonary lesions.
Transbronchial cryobiopsy (transbronchial cryobiopsy) is a minimally invasive technique that yields larger specimens than conventional transbronchial forceps biopsies (transbronchial forceps biopsies) and demonstrates superior diagnostic rates for interstitial lung diseases.
This study aims to examine the diagnostic performance of transbronchial cryobiopsy relative to transbronchial forceps biopsies in peripheral pulmonary lesions.
Between May 2021 and December 2023, patients with peripheral pulmonary lesions were enrolled and underwent transbronchial forceps biopsies followed by transbronchial cryobiopsy.
cryobiopsy found a diagnosis in most patients, more often than forceps biopsy
The study included 84 patients.
The median lesion size was 37 mm (interquartile range: 26, 54), with 16 lesions (19.0%) measuring less than 2.0 cm.
Among the participants, 44 (52.4%) were diagnosed with lung cancer, and 28 (33.3%) had infectious diseases.
The incidence of ≥ grade 3 bleeding was 7.1%.
Transbronchial cryobiopsy significantly improves the diagnostic yield for peripheral pulmonary lesions, irrespective of fluoroscopic guidance, and is effective for both malignant and benign lesions.
Furthermore, it is associated with minimal complications, affirming its safety and efficacy as a diagnostic procedure.
HighlightsTBCB consistently provided a higher pathological yield compared to transbronchial forceps biopsies, independent of lesion size, use of fluoroscopy, or the nature of the pathology (benign or malignant)transbronchial cryobiopsy yielded larger tissue sample and had high successful rates for NGS testing.