Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.

Cohort studySurgical endoscopy· Jun 2026

Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.

Shoma Sasaki, Daichi Kitaguchi, Masaaki Ito … ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery

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Colon & Rectal SurgeryCohort studyTreatmentQ1IF 3.2

Combined oral antibiotics and mechanical bowel preparation linked to lower wound infection odds

Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.

Shoma Sasaki … ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery

Surgical endoscopy · Jun 2026 · Q1 in Surgery

Background

There are concerns regarding postoperative infections following laparoscopic colectomy with intracorporeal anastomosis.

Purpose

Thus, in this study, we aimed to determine the optimal preoperative bowel preparation to reduce postoperative infectious complications in patients undergoing laparoscopic colectomy with intracorporeal anastomosis.

Methods

This secondary analysis of the ICAN study-a multicenter, retrospective cohort study involving 46 institutions affiliated with the Japan Society of Laparoscopic Colorectal Surgery-included 615 patients with colon adenocarcinoma undergoing laparoscopic colectomy with intracorporeal anastomosis between January 2020 and December 2021.

n = 615 patients

Results

combined prep cut wound infection odds after surgery

OR by subgroup · 95% CI

More results

4/156 [2.6%], P = 0.044, odds ratio: 0.125, 95% confidence interval: 0.014-1.109) were lower in the combined preparation group, whereas anastomotic leakage or paralytic ileus did not significantly differ.

More results

The median postoperative hospital stay was significantly shorter in the combined group (8 days [interquartile range, 7-10]) than in the other group (9 days [interquartile range, 7-12]; P < 0.001).

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Conclusion

Combined oral antibiotics and mechanical bowel preparation yields favorable outcomes, including fewer infectious complications and shorter hospital stays, in laparoscopic colectomy with intracorporeal anastomosis.

Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.

Optimal preoperative bowel preparation for intracorporeal anastomosis in laparoscopic colectomy.

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