Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant…

AI / informaticsClinical breast cancer· Aug 2026

Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study.

Jinrui Liu, Mingsong Tang, Fei Jia … Jing Zhang

Breast SurgeryAI / informaticsTreatmentQ2IF 2.7

Combined MRI radiomics-clinical model predicts breast-conserving surgery eligibility after chemotherapy

Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study.

Jinrui Liu … Jing Zhang

Clinical breast cancer · Aug 2026

Background

Neoadjuvant chemotherapy (neoadjuvant chemotherapy) is widely used in the management of breast cancer, as it can downstage tumors and increase the rate of breast-conserving surgery (breast-conserving surgery).

Methods

From Center 1 (n = 227) were randomly divided into a training cohort (n = 181) and an internal validation cohort (n = 46), while data from Center 2 (n = 88) served as an external validation cohort.

n = 315 patients

Results

combined MRI model predicted eligibility well, 1.0 would be perfect

0.91AUC

Training

0.839AUC

Internal validation

0.755AUC

External validation

More results

The overall breast-conserving surgery rate was 73.65% (232/315).

The habitat model achieved AUCs of 0.886, 0.778, and 0.725 in the training, internal validation, and external validation cohorts, respectively.

The clinical-radiological model yielded AUCs of 0.742, 0.733, and 0.707.

“

Conclusion · 1 of 2

The combined model integrating habitat radiomics and clinical-radiological variables demonstrated favorable performance for predicting breast-conserving surgery feasibility after neoadjuvant chemotherapy.

Conclusion · 2 of 2

This noninvasive approach may assist clinicians in preoperative surgical planning and facilitate individualized breast-conserving treatment strategies.

Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study.

Habitat-Based MRI Radiomics for Predicting Breast-Conserving Surgery Feasibility After Neoadjuvant Chemotherapy in Breast Cancer: A Multicenter Study.

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