Sedation Dose of Remimazolam for Older Adults Undergoing Hip Arthroplasty with Neuraxial Anesthesia and Its Impact on Postoperative Delirium.

Compared with saline, the remimazolam groups had lower cortisol and norepinephrine concentrations at operating room exit, whereas within‑group changes from entry to exit did not reach statistical significance (p > 0.05).

Within the observed postoperative delirium incidence range (2.86-6.00%), remimazolam did not appear to increase postoperative delirium over the first 7 postoperative days compared with saline, although the study was not powered to detect modest differences.