Factors Affecting the Occurrence of Hypoxemia During One-Lung Ventilation.

Cohort studyPrilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki)· Nov 2025

Factors Affecting the Occurrence of Hypoxemia During One-Lung Ventilation.

Marija Jovanovski-Srceva, Anita Kokareva, Aleksandra Brzanov-Gavrilovska

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Cardiac & Thoracic AnesthesiaCohort studyPrognosisQ4IF 0.1

Desaturation during one-lung ventilation peaked at 20 minutes, affecting 27.5% of patients.

Factors Affecting the Occurrence of Hypoxemia During One-Lung Ventilation.

Marija Jovanovski-Srceva … Aleksandra Brzanov-Gavrilovska

Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) · Nov 2025

Background

Hypoxemia that occurs during one-lung ventilation (one-lung ventilation) in thoracic surgery increases the risk of perioperative and postoperative complications, affecting mortality and morbidity.

Purpose

The aim of this study is to analyze the occurrence of perioperative hypoxemia (SpO₂ ≤ 90%) and to determine whether preoperative spirometry results and arterial blood gas analyses influence its development.

Methods

In this retrospective study, we evaluated 80 elective patients who underwent lung resection (segmentectomy, lobectomy, bilobectomy, pneumonectomy) due to malignancy under one-lung ventilation.

n = 80 elective patients

27.5%

Results

27.5%

More than a quarter of patients desaturated 20 minutes into one-lung ventilation.

n = 80 elective patients

More results

It was more common in patients with right-sided surgery, patients with FEV₁% ≥ 70 and FVC%≥70, and in overweight patients (BMI ≥ 25).

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Conclusion · 1 of 2

The risk factors for hypoxemia during one-lung ventilation in thoracic surgery include right-sided surgery, which poses higher anatomical challenges for oxygenation, and pulmonary function values such as FEV and FVC at or above 70 percent.

Conclusion · 2 of 2

Additionally, a higher body mass index (BMI) is a key predictor of oxygen saturation drops. These factors highlight the need for careful preoperative assessment to manage oxygenation effectively.

Factors Affecting the Occurrence of Hypoxemia During One-Lung Ventilation.

Factors Affecting the Occurrence of Hypoxemia During One-Lung Ventilation.

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