Body Composition and Psychological Correlates of Resting Energy Expenditure and Activity in Adolescent Girls with Anorexia Nervosa.
Resting energy expenditure is drastically lower in adolescents with anorexia nervosa than peers
Body Composition and Psychological Correlates of Resting Energy Expenditure and Activity in Adolescent Girls with Anorexia Nervosa.
Anorexia Nervosa (Anorexia Nervosa) triggers profound metabolic and psychological adaptations during adolescence.
This study investigated the relationships between resting energy expenditure (resting energy expenditure), body composition, physical activity (physical activity), and specific psychometric phenotypes in adolescent girls with Anorexia Nervosa compared to healthy, normal-weight (normal-weight) peers.
Sixteen adolescent girls with severe Anorexia Nervosa (16.1 ± 1.2 year) and 16 age-matched normal-weight controls (15.6 ± 1.5 year) underwent clinical evaluations: anthropometry, bioelectrical impedance analysis for fat-free mass (fat-free mass) and fat mass (fat mass), indirect calorimetry for resting energy expenditure, the short-form International Physical Activity Questionnaire (International Physical Activity Questionnaire), and the Eating Disorder Inventory-3 (EDI-3).
Girls with Anorexia Nervosa exhibited significantly lower BMI (-20.3%, ES: 1.94, large ), fat-free mass (-18.3%, ES: 1.92, large ), and fat mass (-25.7%, ES: 0.79, medium ) than controls ( p < 0.003).
This hypometabolic state persisted after adjusting resting energy expenditure for body weight (-34.9%) or fat-free mass (-32.5%, p < 0.001), consistent with adaptive thermogenesis.
Adolescents with Anorexia Nervosa exhibit profound metabolic suppression via adaptive thermogenesis, together with an apparent dissociation between walking-related activity and hypotension.
Since cognitive distortions and distress vary independently of anthropometric severity, clinical recovery must extend beyond nutritional rehabilitation; targeted psychotherapy may therefore be necessary to address persistent psychological maladjustment.