Role of transcranial Doppler pulsatility index for predicting neurological deterioration in mild-to-moderate…

Cohort studySaudi journal of anaesthesia· 2026

Role of transcranial Doppler pulsatility index for predicting neurological deterioration in mild-to-moderate traumatic brain injury patients in intensive care unit.

Sachreet Kaur, Nisha Rani

Neurocritical CareCohort studyPrognosisQ2IF 0.9

Admission pulsatility index accurately predicted neurological deterioration after mild-to-moderate traumatic brain injury

Role of transcranial Doppler pulsatility index for predicting neurological deterioration in mild-to-moderate traumatic brain injury patients in intensive care unit.

Sachreet Kaur, Nisha Rani

Saudi journal of anaesthesia · 2026

Background

Traumatic brain injury (traumatic brain injury) is a leading cause of death and long-term disability worldwide, particularly among young adults in low- and middle-income countries.

Methods

Were followed for seven days.

n = 100 adult

Results

higher pulsatility predicted deterioration with strong accuracy, 1.0 would be perfect

OR 4.30 (95% CI 1.70 to 10.80)

null 1

1.70

10.80

CI excludes the null - significant

More results

Neurological deterioration occurred in 22% of patients.

A pulsatility index cutoff value of ≥1.25 yielded a sensitivity of 77% and a specificity of 80%.

On multivariate analysis, admission pulsatility index ≥1.25 independently predicted neurological deterioration (adjusted OR 4.3; 95% CI 1.7-10.8).

“

Conclusion

Admission pulsatility index measured by Transcranial Doppler is a reliable, noninvasive predictor of early neurological deterioration in patients with mild-to-moderate traumatic brain injury and may aid early risk stratification in the intensive care unit.

Role of transcranial Doppler pulsatility index for predicting neurological deterioration in mild-to-moderate traumatic brain injury patients in intensive care unit.

Role of transcranial Doppler pulsatility index for predicting neurological deterioration in mild-to-moderate traumatic brain injury patients in intensive care unit.

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