Factors affecting the likelihood of documented medication concerns in patients with multimorbidity: a…

Cross-sectionalBJGP open· Jan 2026

Factors affecting the likelihood of documented medication concerns in patients with multimorbidity: a cross-sectional study in primary care.

Ileana Gefaell Larrondo, Alba Campillejo García, Almudena Castaño Reguillo … Jaime Barrio Cortes

Chronic Disease ManagementCross-sectionalClinical practiceQ1IF 2.1

Older age is most strongly linked to documented medication concern in multimorbidity

Factors affecting the likelihood of documented medication concerns in patients with multimorbidity: a cross-sectional study in primary care.

Ileana Gefaell Larrondo … Jaime Barrio Cortes

BJGP open · Jan 2026 · Q1 in Family Medicine

Background

High-risk patients with chronic conditions in Primary Care often face medication-related problems.

Purpose

This study aims to describe the characteristics of high-risk patients with chronic conditions in Madrid, Spain, who have documented medications concern and to analyze the associated factors.

Methods

Were identified by the Adjusted Morbidity Groups stratification tool in Primary Care electronic clinical records.

Results

risk of medication concern rises sharply with older age

OR 11 (95% CI 5.40 to 22.30)

null 1

5.40

22.30

CI excludes the null - significant

More results

In all, 40 776 (28.56%) reported medication concern.

Patients with medication concern were older (84.64 vs 72.69 years), had more chronic conditions (7 vs 6) and medications (9.7 vs 8.7).

They were more likely to live alone (8.5% vs 2.7%) and showed higher dependency.

“

Conclusion · 1 of 2

Age, polypharmacy, multimorbidity, and social isolation are predictors of medication concern in high-risk chronic patients in Primary Care.

Conclusion · 2 of 2

Addressing psychological barriers, simplifying treatment, and strengthening social support through tailored interventions could decrease medication concerns.

Factors affecting the likelihood of documented medication concerns in patients with multimorbidity: a cross-sectional study in primary care.

Factors affecting the likelihood of documented medication concerns in patients with multimorbidity: a cross-sectional study in primary care.

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