Hemostatic Response to Palliative Radiotherapy for Bleeding Gastric Cancer and Pretreatment Endoscopic…

Cohort studyInternal medicine (Tokyo, Japan)· Jul 2026

Hemostatic Response to Palliative Radiotherapy for Bleeding Gastric Cancer and Pretreatment Endoscopic Characteristics: A Retrospective Cohort Study.

Kazuya Kimura, Kenta Watanabe, Yuki Wada … Katsunori Iijima

GastroenterologyCohort studyTreatmentQ3IF 0.8

Palliative radiotherapy achieved hemostasis in most patients with bleeding gastric cancer.

Hemostatic Response to Palliative Radiotherapy for Bleeding Gastric Cancer and Pretreatment Endoscopic Characteristics: A Retrospective Cohort Study.

Kazuya Kimura … Katsunori Iijima

Internal medicine (Tokyo, Japan) · Jul 2026 · Q3 in Internal Medicine

Purpose

As no prior studies have examined the association between the pretreatment endoscopic or histopathological findings and the hemostatic efficacy of palliative radiotherapy (pRT), we investigated the predictors of response and rebleeding in gastric cancer (gastric cancer).

Methods

Twenty-three patients with bleeding gastric cancer treated with RT were analyzed.

Results

radiotherapy stopped active bleeding in most patients, without needing rescue treatment

MD 13 (95% CI 0 to 24.60)

null 0

0

24.60

CI crosses the null - not significant

More results

The pretreatment endoscopic and histopathological factors were not associated with the initial response.

Diabetes mellitus was more frequent in non-responders.

Among the responders, a circumferential tumor extent of ≥1/2 of the lumen was significantly associated with earlier rebleeding (median rebleeding-free survival, 9.5 months; p=0.045).

More results

No adverse events of grade ≥3 occurred.

“

Conclusion · 1 of 2

In this exploratory analysis, RT achieved effective hemostasis in patients with bleeding gastric cancer. No pretreatment endoscopic or histological features were significantly associated with the initial hemostatic response.

Conclusion · 2 of 2

Extensive circumferential involvement identified responders at an increased risk of rebleeding, and a higher BED 10 showed a non-significant trend toward improved response without increased toxicity.

Hemostatic Response to Palliative Radiotherapy for Bleeding Gastric Cancer and Pretreatment Endoscopic Characteristics: A Retrospective Cohort Study.

Hemostatic Response to Palliative Radiotherapy for Bleeding Gastric Cancer and Pretreatment Endoscopic Characteristics: A Retrospective Cohort Study.

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