Post

New research · Internal Medicine
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 3h
Cohort studyJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2026

Opioid-induced respiratory depression or oversedation risk assessment in hospitalized patients with cancer receiving palliative care.

Nancy Baballos, Levon S Shahnazarian, Larsa A Goro … Joseph D Ma
Read paper
Internal MedicineCohort study

Opioid-induced respiratory depression/oversedation events were rare in hospitalized cancer patients on opioids in palliative care

Opioid-induced respiratory depression or oversedation risk assessment in hospitalized patients with cancer receiving palliative care.

Nancy Baballos … Joseph D Ma
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners · 2026
Purpose

The Oversedation Risk Criteria (Oversedation Risk Criteria) is a prediction model that estimates prescription opioid-induced respiratory depression (opioid-induced respiratory depression) or oversedation risk in hospitalized patients.

Methods

This single-center, retrospective analysis included patients who were at least 18 years of age, diagnosed with cancer, currently taking an opioid, and completed an initial palliative care consultation from January 1, 2022 to July 31, 2023.

n = 649
0.8%
Results
0.8%
an oversedation event needing naloxone reversal was rare
n = 649
More results

The Oversedation Risk Criteria score (mean ± SD) was 10.6 ± 4.9, which correlated with moderate risk (n = 649).

The number of patients at low, moderate, and high-risk for an opioid-induced respiratory depression/oversedation event was 282 (43%), 356 (55%), and 11 (2%), respectively.

Concurrent sedation medication use was 80% (n = 517).

More results

One-hundred and sixty (25%) and 131 (20%) patients were on a benzodiazepine and a gabapentinoid.

“
Conclusion

Patients with cancer on an opioid who received palliative care are at moderate opioid-induced respiratory depression/oversedation risk during their hospitalization.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Cohort Study
4.5 minutes
Each visual-field test averaged 4.5 minutes per eye.
Review
46.7%
nearly half of thyroid patients had Graves' disease, the most common overactive-thyroid condition
Cross-sectional
MYR 88,346.12
Average annual out-of-pocket expenditure for patients with cancer in Malaysia.
Case-control
5.4% Reduction in Odds of Neuropathy
each rise in zinc levels lowers the chance of nerve damage
Cross-sectional
SIR 9.93
risk climbs sharply when relatives cluster and clotting starts young
Cohort Study
67.8%
one-year survival was far worse than the intermediate-risk group's, roughly one in three died
Systematic Review
“Current evidence does not support universal thromboprophylaxis following ACLR.”