Post

New research · Internal Medicine
Einstein (Sao Paulo, Brazil) · 3h
Cohort studyEinstein (Sao Paulo, Brazil) · 2026

Evaluation of anticoagulation quality in patients with primary antiphospholipid syndrome at a tertiary hospital.

Renata Lys Pinheiro de Mello, Maria Eugênia Teixeira Bicalho, Gustavo Guimarães Moreira Balbi … Danieli Castro Oliveira de Andrade
Read paper
Internal MedicineCohort study

Only 34.4% of primary antiphospholipid syndrome patients had adequate anticoagulation control

Evaluation of anticoagulation quality in patients with primary antiphospholipid syndrome at a tertiary hospital.

Renata Lys Pinheiro de Mello … Danieli Castro Oliveira de Andrade
Einstein (Sao Paulo, Brazil) · 2026
Purpose

This study aimed to evaluate the quality of anticoagulation control in patients with primary antiphospholipid syndrome, using time in therapeutic range.

Methods

Anticoagulation quality was assessed in a retrospective study including patients with primary Antiphospholipid Syndrome.

n = 93 patients
Results
34.4%
just over a third stayed safely anticoagulated, most were not
n = 93 patients
More results

Among these, 32 patients (74.4 achieved time in therapeutic range ≥60%, with a median time in therapeutic range of 89.3%.

However, 61 patients (65.6%) had insufficient follow-up, resulting in an incalculable time in therapeutic range.

More results

No significant differences were observed between patients with good and poor anticoagulation control regarding demographic or clinical variables.

“
Conclusion · 1 of 2

Our findings indicates that only 34.4% of patients with primary antiphospholipid syndrome achieved adequate anticoagulation control and inadequate follow-up remains a major barrier.

Conclusion · 2 of 2

Further studies are needed to identify factors contributing to suboptimal time in therapeutic range and to improve anticoagulation management in this high-risk population.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
Cohort Study
13.5%
Central retinal artery peak blood-flow speed was 13.5% lower in diabetic patients.
Cohort Study
4.5 minutes
Each visual-field test averaged 4.5 minutes per eye.
Review
46.7%
nearly half of thyroid patients had Graves' disease, the most common overactive-thyroid condition
Cross-sectional
MYR 88,346.12
Average annual out-of-pocket expenditure for patients with cancer in Malaysia.
Case-control
5.4% Reduction in Odds of Neuropathy
each rise in zinc levels lowers the chance of nerve damage
Cross-sectional
SIR 9.93
risk climbs sharply when relatives cluster and clotting starts young
Cohort Study
67.8%
one-year survival was far worse than the intermediate-risk group's, roughly one in three died
Systematic Review
“Current evidence does not support universal thromboprophylaxis following ACLR.”