Thromboprophylaxis After ACL Reconstruction: Controversies and Future Challenges.
Current evidence does not support universal thromboprophylaxis following anterior cruciate ligament reconstruction.
Thromboprophylaxis After ACL Reconstruction: Controversies and Future Challenges.
Anterior cruciate ligament reconstruction (anterior cruciate ligament reconstruction) is a very common procedure in young, active individuals.
This review aims to summarize key international recommendations to support clinical decision-making.
Rather than performing a systematic review, relevant documents were identified from official publications, consensus statements, and registry-based recommendations issued by recognized orthopaedic and thrombosis-related organizations.
This narrative review identified nine major international guidelines addressing thromboprophylaxis in anterior cruciate ligament reconstruction.
Most guidelines, including CHEST and NICE, advise against routine anticoagulation for low-risk patients, reserving it for those with specific risk factors.
While ICM-VTE supports the use of aspirin or LMWH in high-risk cases, SFAR stands out by recommending routine LMWH for all patients.
HAOST emphasizes early mobilization and selective prophylaxis, including aspirin for low-risk groups.
Current evidence does not support universal thromboprophylaxis following anterior cruciate ligament reconstruction.
A risk-stratified approach is recommended, with mechanical measures or aspirin for low-to-moderate-risk patients and LMWH or DOACs for high-risk individuals.
Future research may focus on genetic and patient-specific factors to better explain existing heterogeneity.