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New research · Ophthalmology
Aesthetic plastic surgery · 11h
Cohort studyAesthetic plastic surgery · 2026

Upper Blepharoplasty Under Anticoagulant or Antiplatelet Therapy: Is Safety Still a Concern?

Juan A Viscardi, Salvatore Giordano
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OphthalmologyCohort study

Complication rates similar with or without continued blood thinners for eyelid surgery

Upper Blepharoplasty Under Anticoagulant or Antiplatelet Therapy: Is Safety Still a Concern?

Juan A Viscardi, Salvatore Giordano
Aesthetic plastic surgery · 2026
Background

Dermatochalasis is defined as a skin excess in the upper or lower eyelid which may be associated with orbital fat prolapse, lacrimal gland prolapse, and involutional blepharoptosis.

Purpose

This study aimed to investigate the safety of upper blepharoplasty in patients receiving antithrombotic therapy.

Methods

The cohort was stratified into two groups: a study group of 100 patients on anticoagulant/antiplatelet therapy (including aspirin, warfarin, and apixaban) and a control group of 292 patients not on such therapy.

n = 292 patients
Results

checked complications after surgery, similar with either choice

OR 2.90 (95% CI 0.29 to 28.56)
null 1
0.29
28.56
CI crosses the null - not significant
More results

Baseline characteristics differed significantly between groups, with patients on anticoagulant/antiplatelet therapy being older and having higher comorbidity rates.

Notably, no major bleeding events occurred.

Patient-reported and surgeon-assessed satisfaction scores were high and similar between groups.

More results

On multivariable logistic regression analysis, no variable was identified as a significant independent predictor of complications; however, hypertension demonstrated the highest odds ratio (OR 2.9, 95% CI 0.29-28.56, p=0.370).

“
Conclusion · 1 of 3

Upper blepharoplasty appears to be safely performed in carefully selected patients receiving anticoagulant or antiplatelet therapy.

Conclusion · 2 of 3

In this retrospective cohort, continuation of antithrombotic therapy was not associated with an increased rate of detected complications compared with controls.

Conclusion · 3 of 3

These findings support the feasibility of maintaining therapy in appropriately selected cases, although larger prospective studies are required to confirm these observations.

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