Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura. | ScholarDeck

Paper

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

New research · Ophthalmology

Orbit (Amsterdam, Netherlands) · 1mo

StudyOrbit (Amsterdam, Netherlands)· Jun 2026

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

Henry Bair, Mišo Gostimir, Jurij R Bilyk … Charlotte L Marous

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OculoplasticsStudyQ3IF 1.0

Bone marrow had 8%-10% clonal plasma cells, favoring solitary extramedullary plasmacytoma

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

Henry Bair … Charlotte L Marous

Orbit (Amsterdam, Netherlands) · Jun 2026 · Q3 in Ophthalmology

Background

Extramedullary plasmacytoma of the orbit is rare and usually occurs with multiple myeloma.

Results

to 10%

8-10 out of 100 marrow cells were abnormal - low enough to favor a single tumor, not widespread cancer

More results

We report an incidentally discovered asymptomatic orbital and dural plasmacytoma in a 71-year-old man evaluated after a fall.

Serum studies identified an IgG-kappa monoclonal gammopathy, and dural biopsy revealed a kappa-restricted CD138-positive plasma-cell neoplasm.

More results

The patient received external-beam radiotherapy to the orbit and involved dura (45 Gy) with marked radiographic improvement.

At 1 year, he retained 20/20 vision, full extraocular motility, and no evidence of progression.

“

Conclusion

This case highlights that even extensive orbital plasmacytoma may remain clinically silent and that prompt biopsy, staging, and radiotherapy can preserve excellent function.

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