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StudyOrbit (Amsterdam, Netherlands) · 2026

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

Henry Bair, Mišo Gostimir, Jurij R Bilyk … Charlotte L Marous

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OphthalmologyStudy

Bone marrow had 8%-10% clonal plasma cells, favoring solitary extramedullary plasmacytoma

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

Henry Bair … Charlotte L Marous

Orbit (Amsterdam, Netherlands) · 2026

Background

Extramedullary plasmacytoma of the orbit is rare and usually occurs with multiple myeloma.

Results

8%

to 10%

8-10 out of 100 marrow cells were abnormal - low enough to favor a single tumor, not widespread cancer

More results

We report an incidentally discovered asymptomatic orbital and dural plasmacytoma in a 71-year-old man evaluated after a fall.

Serum studies identified an IgG-kappa monoclonal gammopathy, and dural biopsy revealed a kappa-restricted CD138-positive plasma-cell neoplasm.

More results

The patient received external-beam radiotherapy to the orbit and involved dura (45 Gy) with marked radiographic improvement.

At 1 year, he retained 20/20 vision, full extraocular motility, and no evidence of progression.

“

Conclusion

This case highlights that even extensive orbital plasmacytoma may remain clinically silent and that prompt biopsy, staging, and radiotherapy can preserve excellent function.

Post

Incidentally discovered asymptomatic extramedullary plasmacytoma involving the orbit and dura.

Bone marrow had 8%-10% clonal plasma cells, favoring solitary extramedullary plasmacytoma

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