Metagenomic next-generation sequencing in diagnosing rhino-orbital-cerebral mucormycosis presenting as cerebral Infarction: a case series and diagnostic analysis of seven patients.

Rhino-orbital-cerebral mucormycosis should be highly suspected in diabetic patients presenting with acute cerebral infarction accompanied by fever and facial or ocular symptoms.

mNGS enables rapid and early etiological diagnosis of rhino-orbital-cerebral mucormycosis, which is crucial for improving outcomes.

Earlier diagnosis, combined antifungal therapy, and surgical intervention may be associated with better prognosis.