Ocular neuromyotonia has been reported in only seven prior thyroid eye disease cases.
Ocular Neuromyotonia in Thyroid Eye Disease.
André Sobral-Pinho … João Lemos
Neuro-ophthalmology (Aeolus Press) · 2026
Background
Ocular neuromyotonia (ocular neuromyotonia) in thyroid eye disease (thyroid eye disease) seems to be a rare finding.
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Results
7
TED cases
Ocular neuromyotonia in thyroid eye disease is rare, with only seven cases described.
n = 7 TED cases
More results
We present the case of a 61-year-old male thyroid eye disease patient who developed spontaneous transient neuromyotonic infradeviation of the right eye every ~1 minute in the setting of prominent enlargement of the right inferior rectus muscle and restriction of supraduction.
Neither carbamazepine or lacosamide were able to abate ocular neuromyotonia.
More results
Following subsequent thyroid eye disease worsening with almost complete restriction of the right eye, ocular neuromyotonia was no longer observed.
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Conclusion · 1 of 2
Newer neuronal membrane stabilizers acting on sodium and calcium channels (e.g. lamotrigine, oxcarbazepine) as well as newer monoclonal antibodies (e.g.
Conclusion · 2 of 2
teprotumumab, tocilizumab, infliximab) might play a role in thyroid eye disease-related ocular neuromyotonia and their potential therapeutic effect should be investigated in future studies.