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New research · Ophthalmology
The American journal of emergency medicine · 12h
Cohort studyThe American journal of emergency medicine · 2026

Evaluation of acute visual changes in the pediatric emergency department: Etiologies and red flags.

Bilge Akkaya, Ahmet Serkan Özcan, Fatma Şule Erdem … Nilden Tuygun
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OphthalmologyCohort study

Among children imaged for acute visual changes, 35% had pathologic neuroimaging findings

Evaluation of acute visual changes in the pediatric emergency department: Etiologies and red flags.

Bilge Akkaya … Nilden Tuygun
The American journal of emergency medicine · 2026
Background

Acute visual changes-including blurred vision, diplopia, photopsia, visual hallucinations, and vision loss-pose a diagnostic challenge in children due to limited symptom description and limited cooperation during examination.

Purpose

We aimed to (1) characterize the etiologies of children presenting to a pediatric emergency department (pediatric emergency department) with acute visual changes and (2) identify clinical predictors of pathologic neuroimaging findings.

Methods

Aged 1 month to 18 years were identified through structured chief complaint fields and keyword searches of electronic medical records (e.g., "blurred vision," "vision loss," "double vision").

n = 444 patients
35%
Results
35%
about 1 in 3 children scanned had a brain problem found on imaging
n = 444 patients
More results

We included 444 patients in the study.

The most common etiologies were neurological (29%), ocular (23%), and systemic (18%).

More results

Vision loss, pain with eye movements, focal neurological deficits, signs of meningeal irritation, dysmetria, tremor, papilledema, abnormal pupillary light reflexes, and a positive Romberg sign were significantly more frequent among patients with pathologic neuroimaging findings (p < 0.001).

“
Conclusion · 1 of 3

Although most pediatric acute visual changes are benign, a clinically important proportion are associated with significant neuroimaging abnormalities.

Conclusion · 2 of 3

Specific neurological examination findings may help identify children at higher risk for intracranial pathology.

Conclusion · 3 of 3

Prospective multicenter studies are needed to validate these predictors and refine imaging strategies in the pediatric emergency department.

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