Leptospiral uveitis: A late complication of systemic leptospirosis.

Cohort studyThe Indian journal of medical research· Apr 2026

Leptospiral uveitis: A late complication of systemic leptospirosis.

S R Rathinam, Rajesh Vedhanayagi, Radhika T Thundikandy … Jeya Kohila

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UveitisCohort studyDiagnosisQ2IF 1.6

Most eyes with leptospiral uveitis gained two or more lines of vision after steroid treatment

Leptospiral uveitis: A late complication of systemic leptospirosis.

S R Rathinam … Jeya Kohila

The Indian journal of medical research · Apr 2026 · Q2 in General Medicine

Background

And objectives Leptospirosis is an important animal borne disease that primarily affects farmers in tropical countries.

Methods

In this retrospective observational study, we have reviewed the data from clinical and laboratory records of microscopic agglutination test (microscopic agglutination test) positive, uveitis patients seen between 1994 and 2017 at the uveitis department of a university affiliated ophthalmology postgraduate institute in Tamil Nadu, South India.

n = 1224 eyes

Results

94.5%

nearly all eyes saw noticeably better after steroid treatment

n = 1224 eyes

More results

Out of a total of 75,150 new uveitis cases with different aetiologies seen in 24 years, 3,658 (4.9%) had clinical diagnosis of leptospiral uveitis.

Of them, 1,268 (34.7%) patients were positive for leptospiral serological test.

Of 876, 650 (74.2%) were men, 482 (55%) were farmers.

More results

Inflammatory control was achieved in 96% of the patients.

“

Conclusion

Recognition of this entity is vital, especially in young males in whom other immunological uveitis are also common.

Leptospiral uveitis: A late complication of systemic leptospirosis.

Leptospiral uveitis: A late complication of systemic leptospirosis.

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