Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious…

Cohort studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie· May 2026

Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan.

Chung-Hao Hsiao, Hung-Ju Chen, Chia-Jen Chang … Wen-Jung Lo

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UveitisCohort studyTreatmentQ1IF 3.1

About half of patients had improved vision after vitrectomy for endophthalmitis

Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan.

Chung-Hao Hsiao … Wen-Jung Lo

Graefe's archive for clinical and experimental ophthalmology · May 2026 · Q1 in Ophthalmology

Purpose

To evaluate long-term visual outcomes and prognostic factors after small-gauge pars plana vitrectomy (pars plana vitrectomy) for exogenous endophthalmitis.

Methods

Single-center, retrospective cohort of 45 eyes (45 patients) undergoing pars plana vitrectomy for exogenous endophthalmitis (June 2014-September 2024).

n = 45 eyes

51.1%

Results

51.1%

just over half of patients saw their vision get better after surgery

n = 45 eyes

More results

Median BCVA improved from hand motion (~ 20/4000; logMAR 2.30) to approximately 20/1200 (logMAR 1.78; p = 0.004).

Factors associated with worse final BCVA included poorer initial BCVA (p = 0.002), culture positivity (p = 0.037), and intraoperative retinal detachment (p = 0.009).

More results

Favorable factors were 27-gauge pars plana vitrectomy (p = 0.044) and post-cataract etiology (p = 0.006).

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Conclusion · 1 of 4

Small-gauge pars plana vitrectomy, including 27-gauge, was associated with meaningful visual improvement in exogenous endophthalmitis.

Conclusion · 2 of 4

Final visual outcomes appeared to be influenced by baseline vision, microbial virulence, and the presence of retinal detachment.

Conclusion · 3 of 4

However, given the highly heterogeneous nature of this cohort, these findings should be interpreted with caution and may warrant further validation.

Conclusion · 4 of 4

Our findings provide contemporary data complementing the Endophthalmitis Vitrectomy Study and reflect outcomes achievable with modern techniques.

Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan.

Long-term outcomes and factors associated with visual recovery after small-gauge vitrectomy for infectious endophthalmitis: a 10-year experience at a single tertiary center in Taiwan.

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