Comparison of Clinical Outcomes of Intravitreal 0.625% Povidone-Iodine versus Antibiotic Injection for Postoperative Endophthalmitis.

Intravitreal 0.625% povidone-iodine injection was associated with fewer intravitreal injections, shorter hypopyon duration, and more favorable visual outcome-related measures, including significant visual improvement from baseline and a lower frequency of severe visual impairment, compared with intravitreal antibiotic treatment.

These findings suggest that povidone-iodine may be considered a safe and effective initial treatment option for postoperative endophthalmitis. Further prospective studies are needed to validate these results.