Deep Learning-Based Diagnostic Model for Ocular Surface Neoplastic Diseases.
Deep learning model diagnosed ocular surface tumors more accurately than ophthalmologists and residents.
Deep Learning-Based Diagnostic Model for Ocular Surface Neoplastic Diseases.
To develop a deep learning (deep learning) model for diagnosing ocular surface tumors and evaluating its diagnostic performance.
A total of 1491 ocular surface images representing 7 diseases-nevus (28 eyes), limbal dermoid (144), MALT lymphoma (20), ocular surface squamous neoplasia (OSSN; 138), melanoma (14), pinguecula (29), and pterygium (1,118)-were captured using slit-lamp microscopy.
the model correctly identified the tumor type almost every time
Disease-specific PPVs were: nevus 75.0%, limbal dermoid 93.5%, MALT lymphoma 57.9%, OSSN 87.0%, melanoma 38.5%, pinguecula 82.1%, and pterygium 96.7%.
The area under the curve (AUC) was: nevus 0.897 (95% confidence interval [CI], 0.810-0.983), limbal dermoid 0.998 (95% CI, 0.996-1.000), MALT lymphoma 0.894 (95% CI, 0.794-0.993), OSSN 0.954 (95% CI, 0.933-0.975), melanoma 0.966 (95% CI, 0.919-1.000), pinguecula 0.954 (95% CI, 0.912-0.995), and pterygium 0.984 (95% CI, 0.976-0.992).
The deep learning model demonstrated high diagnostic accuracy for common ocular surface tumors such as pterygium and limbal dermoid, while diagnostic performance for rare malignancies, including melanoma and MALT lymphoma, remains limited and requires further refinement.
SYNOPSIS: We developed a deep learning model that demonstrated promising performance in identifying ocular surface neoplastic diseases, suggesting its potential as a supportive diagnostic tool in ophthalmic practice.