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New research · Ophthalmology
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 14h
Cohort studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026

Efficacy and safety of gonioscopy-assisted transluminal trabeculotomy in glaucoma secondary to fuchs uveitis syndrome: a multicenter study.

Merve Oral, Ahmet Yucel Ucgul, Ali Olgun … Zeynep Aktas
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OphthalmologyCohort study

Trabeculotomy sharply cut medication burden in Fuchs uveitis glaucoma eyes

Efficacy and safety of gonioscopy-assisted transluminal trabeculotomy in glaucoma secondary to fuchs uveitis syndrome: a multicenter study.

Merve Oral … Zeynep Aktas
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
Purpose

To evaluate the long-term surgical outcomes of gonioscopy-assisted transluminal trabeculotomy (gonioscopy-assisted transluminal trabeculotomy) in patients with Fuchs uveitis syndrome (fuchs uveitis syndrome)-associated open-angle glaucoma.

Methods

In this multicenter, retrospective, non-comparative study, 34 consecutive eyes of 31 patients with open-angle glaucoma secondary to fuchs uveitis syndrome who underwent gonioscopy-assisted transluminal trabeculotomy at three tertiary referral centers were included.

n = 31 patients
70.4%
Results
70.4%
reduction
fewer glaucoma eye drops needed after surgery
n = 31 patients
More results

Mean preoperative IOP was 34.9 ± 8.0 mmHg on 3.5 ± 0.7 medications.

The cumulative probability of qualified success was 88.2%, and complete success was 41.2% at 24 months.

Hyphema occurred in 14.7% of eyes, and IOP spikes were observed in 14.7%; all were transient.

Four eyes (11.8%) required additional glaucoma surgery.

“
Conclusion · 1 of 2

Gonioscopy-assisted transluminal trabeculotomy appears to be a safe and effective surgical option for achieving sustained IOP reduction and decreasing medication burden in fuchs uveitis syndrome-associated glaucoma.

Conclusion · 2 of 2

Its minimally invasive and conjunctival-sparing nature makes it a reasonable initial surgical strategy in selected patients.

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