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Cohort studyClinical ophthalmology (Auckland, N.Z.) · 2026

One-Year Outcome of PreserFlo MicroShunt Implantation in Patients with Open Angle Glaucoma: Real-World Data from a Tertiary Centre.

Teck Chee Cheng, Khai Voon Ng, Jemaima Che Hamzah

OphthalmologyCohort study

PreserFlo MicroShunt was linked to lower intraocular pressure one year after surgery for open angle glaucoma.

One-Year Outcome of PreserFlo MicroShunt Implantation in Patients with Open Angle Glaucoma: Real-World Data from a Tertiary Centre.

Teck Chee Cheng … Jemaima Che Hamzah

Clinical ophthalmology (Auckland, N.Z.) · 2026

Purpose

To evaluate the one-year clinical outcomes, safety profile, and surgical success of the PreserFlo ® MicroShunt in patients with glaucoma treated at a tertiary referral centre in Malaysia.

Methods

This retrospective study included 40 eyes of 31 patients undergoing PreserFlo MicroShunt implantation performed by two experienced surgeons using a standard ab-externo technique with mitomycin C (0.04% for 3 minutes) and a structured postoperative corticosteroid tapering regimen.

n = 40 eyes

Results

average eye pressure checked one year after surgery, much lower than before

More results

The median number of glaucoma medications decreased from 3.8 to 0.2 drops.

At one-year, complete surgical success was achieved in 82.5% of eyes, while qualified success was 95.0%.

Surgical failure occurred in 5.0% of eyes.

More results

Early postoperative hypotony (IOP ≤5 mmHg) occurred in 17.5%, with persistent hypotony at one year in 2.5%, none of which resulted in vision loss.

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Conclusion · 1 of 3

PreserFlo MicroShunt implantation was associated with reductions in IOP and glaucoma medication burden at one year, with generally acceptable short-term safety outcomes.

Conclusion · 2 of 3

These findings support its role as an effective bleb-forming minimally invasive glaucoma surgery option for patients requiring lower target IOPs, including those with advanced glaucoma.

Conclusion · 3 of 3

However, the results should be interpreted in the context of the modest sample size, retrospective design, absence of a comparator group, and need for postoperative interventions.

Post

One-Year Outcome of PreserFlo MicroShunt Implantation in Patients with Open Angle Glaucoma: Real-World Data from a Tertiary Centre.

PreserFlo MicroShunt was linked to lower intraocular pressure one year after surgery for open angle glaucoma.

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