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New research · Ophthalmology
Cureus · 16h
Case reportCureus · 2026

Suspected Secondary Intraocular Lymphoma With Choroidal Involvement Following Testicular Diffuse Large B-cell Lymphoma: A Case Report.

Battuya Ganbold, Bayasgalan Purevdorj, Quan Dong Nguyen, Dariimaa Ganbat
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OphthalmologyCase report

Flow cytometry found an abnormal B-cell population confirming suspected intraocular lymphoma relapse.

Suspected Secondary Intraocular Lymphoma With Choroidal Involvement Following Testicular Diffuse Large B-cell Lymphoma: A Case Report.

Battuya Ganbold … Dariimaa Ganbat
Cureus · 2026
Background

Secondary intraocular lymphoma is an uncommon manifestation of systemic lymphoma and may relapse in immune-privileged sites years after apparent remission.

45.2%
Results
45.2%
flow cytometry found abnormal lymphoma cells in nearly half of eye cells tested
More results

We report the case of a 67-year-old man with a history of right testicular diffuse large B-cell lymphoma (diffuse large B-cell lymphoma) treated with orchiectomy and systemic chemotherapy who presented five years later with painless progressive vision loss in the left eye.

More results

Examination revealed visual acuity of 20/80, fibrinoid material with hemorrhage in the anterior chamber, and yellow-white choroidal infiltrates extending from the optic disc toward the periphery with associated subretinal fluid.

Multimodal imaging demonstrated subretinal infiltrates and diffuse choroidal thickening.

“
Conclusion

This case highlights the importance of long-term ophthalmic surveillance in patients with testicular diffuse large B-cell lymphoma and the integration of multimodal imaging, ocular fluid analysis, and systemic restaging in the evaluation of suspected ocular relapse.

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