Monte Carlo simulation of uveal melanoma treatment by ocular plaque brachytherapy using gold nanoparticles.

One of its treatment methods involves the use of radioactive seeds, which are temporarily attached to a plaque and placed on the eye.

The dose distribution around the seeds used in ocular plaques strongly depends on the seeds' structure and the ocular plaque's design.

The results show that the average doses received by the different eye structures and the tumour vary depending on the seed model.

The tumour apex dose increases with increasing concentration of gold nanoparticles within the tumour volume, hence reducing the irradiation time.