Etiologic spectrum and predictors of visual acuity in non-glaucomatous optic atrophy.
Ischemic optic neuropathy was the most common cause of non-glaucomatous optic atrophy.
Etiologic spectrum and predictors of visual acuity in non-glaucomatous optic atrophy.
To determine the prevalence and underlying causes of nonglaucomatous optic atrophy (nonglaucomatous optic atrophy) in a tertiary referral center in southeastern Iran and to identify predictors of current visual acuity in this population.
In this descriptive cross-sectional study, patients with a confirmed diagnosis of nonglaucomatous optic atrophy were included.
ischemic causes were behind nearly 1 in 3 optic atrophy cases
Overall, 75 patients (48.4%) had a best-corrected visual acuity (BCVA) of ≥ 1.90 logMAR (logarithm of the minimum angle of resolution), corresponding to counting fingers vision or worse.
Patients with toxic optic neuropathy demonstrated the poorest visual outcomes, with 5 of 6 cases (83.3%) having a BCVA of ≥ 1.90 logMAR.
Traumatic optic neuropathy was the second most common cause, observed in 37 patients (23.9%).
In multivariate analysis, a longer duration from symptom onset was the sole independent predictor of poorer current visual acuity (β = 0.253, P = 0.010).
Previous non-arteritic anterior ischemic optic neuropathy was the most common cause of nonglaucomatous optic atrophy in this cohort, followed by traumatic optic neuropathy. Toxic exposure was associated with the poorest visual acuities.
Among all evaluated variables, the duration from symptom onset was the only independent predictor of current visual acuity.