Clinical characteristics, management, and outcomes of pediatric non-infectious uveitis: A multicenter study in Saudi Arabia.
Most children with non-infectious uveitis reached remission within 2 years of treatment.
Clinical characteristics, management, and outcomes of pediatric non-infectious uveitis: A multicenter study in Saudi Arabia.
Pediatric non-infectious uveitis is a challenging condition with significant risks for long-term ocular complications and visual impairment.
This study aimed to describe the clinical features, management strategies, and outcomes of pediatric non-infectious uveitis in two major medical centers in Saudi Arabia.
A retrospective observational study was conducted, including 36 pediatric patients diagnosed with non-infectious uveitis from January 2017 to December 2023.
Among the 36 patients, 66.67% were female, and the mean age at diagnosis was 8.99 ± 4.17 years.
The most common etiology was juvenile idiopathic arthritis (52.8%), followed by idiopathic uveitis (25%) and Vogt-Koyanagi-Harada disease (19.4%).
Bilateral involvement was present in 55.6% of cases, with anterior uveitis being the predominant type (75%).
Antinuclear antibody (antinuclear antibody) positivity was observed in 69.44% of patients.
Pediatric non-infectious uveitis in Saudi Arabia mirrors global patterns, with JIA being the leading cause. Early diagnosis and biologic therapies have improved remission rates and reduced complications.
Future efforts should focus on enhancing screening, patient adherence, and access to advanced therapies to optimize outcomes for affected children.