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Case reportJournal of cancer research and therapeutics · 2026

Leiomyosarcoma of the orbit: A case report and review of literature.

Anjali V Ramdulari, Aswin Ravi, Astha Srivastava, Rambha Pandey

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OphthalmologyCase report

15% of orbital leiomyosarcoma patients had childhood retinoblastoma history.

Leiomyosarcoma of the orbit: A case report and review of literature.

Anjali V Ramdulari … Rambha Pandey

Journal of cancer research and therapeutics · 2026

Results

childhood eye-cancer history was uncommon among these patients

Surgery

84%

Radiotherapy

42%

Childhood RB history

15%

More results

Sarcomas account for 1% of adult malignancies, and 80% of them arise from soft tissue.

Orbital leiomyosarcoma is an extremely rare tumor with less than 40 cases reported.

The most common subsite is the conjunctiva, followed by the eyelid.

More results

A review of the literature on patients with orbital leiomyosarcoma was done, out of which 84% of patients underwent surgery and 42% of patients received radiotherapy.

“

Conclusion

All patients with childhood retinoblastoma had bilateral disease and a history of childhood radiotherapy for retinoblastoma.

Post

Leiomyosarcoma of the orbit: A case report and review of literature.

15% of orbital leiomyosarcoma patients had childhood retinoblastoma history.

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