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New research · Ophthalmology
International journal of ophthalmology · 1d
Cohort studyInternational journal of ophthalmology · 2026

Clues to prognosis in anterior ischemic optic neuropathy: an optical coherence tomography angiography study.

Maria J Rodrigo, Diego Fernandez-Velasco, Pablo Pérez-Gómez … Elena Garcia-Martin
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OphthalmologyCohort study

Optic nerve blood flow measures strongly predict 1-month vision after ischemic optic neuropathy.

Clues to prognosis in anterior ischemic optic neuropathy: an optical coherence tomography angiography study.

Maria J Rodrigo … Elena Garcia-Martin
International journal of ophthalmology · 2026
Purpose

To investigate optic nerve vascularization in patients with anterior ischemic optic neuropathy (anterior ischemic optic neuropathy) during the first 3mo after onset, using comprehensive ophthalmic assessments combined with optical coherence tomography (optical coherence tomography) and optical coherence tomography angiography (optical coherence tomography-A).

Methods

A prospective longitudinal observational study was performed with a 3-month follow-up.

n = 12 patients
Results
r=0.800
higher blood-flow scores strongly matched better vision measured a month later
n = 12 patients
More results

Mean age was 63.75±8.32y in the anterior ischemic optic neuropathy group and 61.80±5.04y in the control group ( P =0.365).

Gender and laterality distributions were comparable.

Anterior ischemic optic neuropathy patients showed significantly decreased optic nerve head perfusion at baseline ( P =0.024) and 1mo ( P =0.033).

More results

Optical coherence tomography revealed early thickening and subsequent atrophy of the peripapillary retinal nerve fiber layer and macular layers.

“
Conclusion

Vascular parameters derived from optical coherence tomography angiography can act as predictive markers for medium-term visual and structural outcomes in patients with ischemic optic neuropathy.

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