Management of Retinoblastoma: A Challenge in Pediatric Ophthalmology.

ReviewLife (Basel, Switzerland)· Apr 2026

Claudia Carolina Cruz-Gálvez, Víctor Manuel Villar-Calvo, Juan Carlos Ordaz-Favila … Vanessa Bosch-Canto

Pediatric OphthalmologyReviewQ1IF 4.3

Timely detection and proper treatment give retinoblastoma patients up to 98% survival.

Claudia Carolina Cruz-Gálvez … Vanessa Bosch-Canto

Life (Basel, Switzerland) · Apr 2026

Background

Retinoblastoma (Rb) is the most common intraocular malignancy.

Results

98%

children whose retinoblastoma is caught and treated early usually survive

More results

If left untreated, Rb can result in death within 1-2 years.

The primary goal of Rb treatment is to eliminate cancer and save the patient's life, while the second goal includes preserving the eye and vision.

There are several treatment options available for Rb.

More results

The PubMed database was utilized to identify relevant references published during the last 35 years.

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Conclusion

This article shows basic and current concepts on managing Rb, which encompasses diagnosis, evaluation, treatment, follow-up, and challenges.