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New research · Ophthalmology
Ocular oncology and pathology · 1d
Cohort studyOcular oncology and pathology · 2026

Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome: Correlation between Clinical Features, Imaging, and Treatment Response.

Dibya Prabha, Sirisha Senthil, Swathi Kaliki, Vishal Raval
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OphthalmologyCohort study

Most eyes with Sturge-Weber-related choroidal hemangioma had poor final vision despite treatment

Diffuse Choroidal Hemangioma in Sturge-Weber Syndrome: Correlation between Clinical Features, Imaging, and Treatment Response.

Dibya Prabha … Vishal Raval
Ocular oncology and pathology · 2026
Background

The aim of this study was to describe the clinical features, multimodal imaging characteristics, treatment outcomes, and prognostic factors in patients with diffuse choroidal hemangioma (diffuse choroidal hemangioma) associated with Sturge-Weber syndrome (Sturge-Weber syndrome)/phakomatosis pigmentovascularis (phakomatosis pigmentovascularis) at a referral center in India.

Methods

A retrospective observational study was conducted between 2013 and 2024 on patients diagnosed with Sturge-Weber syndrome/phakomatosis pigmentovascularis and associated diffuse choroidal hemangioma.

n = 32 eyes
Results

despite treatment, most eyes still ended with poor vision

22%
Complete tumor regress
69%
Poor visual outcome
More results

The mean age at presentation was 25.3 ± 11.6 years, with a female predominance (59%).

Most patients had Sturge-Weber syndrome (90%), while 10% had phakomatosis pigmentovascularis.

The mean tumor basal diameter and thickness were 8.31 mm and 4.16 mm at presentation.

More results

On multivariate analysis, persistent tumor ( p = 0.008) and tumor recurrence ( p = 0.03) were independent predictors of poor outcome.

“
Conclusion · 1 of 2

Diffuse choroidal hemangioma in Sturge-Weber syndrome is a vision-threatening condition requiring individualized multimodal treatment.

Conclusion · 2 of 2

Although anatomical and visual improvement is achievable, recurrence and tumor persistence are common and predict poor outcomes. Thus, long-term follow-up and early intervention are critical for optimal management.

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