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Cross-sectionalInternational journal of dermatology · 2026

The Association Between Vitiligo and Uveitis: A Large Population-Based Study.

Oran Mann, Sapir Glazer Levavi, Arnon D Cohen … Shany Sherman

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OphthalmologyCross-sectional

Vitiligo is linked to higher odds of uveitis, a vision-threatening eye inflammation.

The Association Between Vitiligo and Uveitis: A Large Population-Based Study.

Oran Mann … Shany Sherman

International journal of dermatology · 2026

Background

Vitiligo is a common acquired immune-mediated skin disease, often associated with other systemic inflammatory conditions.

Purpose

This study sought to investigate the association between vitiligo and uveitis.

Methods

A large population-based cross-sectional study was conducted.

n = 114,609 control

Results

vitiligo patients had higher odds of developing uveitis, sight-threatening eye inflammation

OR 1.30 (95% CI 1.03 to 1.64)

null 1

1.03

1.64

CI excludes the null - significant

More results

The study population included 24,398 consecutive patients with vitiligo and 114,609 control subjects.

The estimated prevalence of uveitis was 0.53% and 0.39%, respectively.

More results

On multivariate analysis, there was an independent association between vitiligo and uveitis (OR 1.30; 95% CI 1.03-1.64, p = 0.024) regardless of a history of uveitis-associated conditions (inflammatory bowel disease, sarcoidosis).

“

Conclusion · 1 of 2

Vitiligo is associated with an increased prevalence of uveitis. Dermatologists should be alert to this potential comorbidity because a coordinated multidisciplinary approach is essential to prevent long-term ocular sequelae.

Conclusion · 2 of 2

Large prospective studies are needed to corroborate these findings.

Post

The Association Between Vitiligo and Uveitis: A Large Population-Based Study.

Vitiligo is linked to higher odds of uveitis, a vision-threatening eye inflammation.

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