Role of Insulin-like growth factor-1 and postnatal growth failure in retinopathy of prematurity development in babies weighing less than 1500 grams at birth - A prospective cohort study.

The median IGF-1 levels were lower in the babies with any stage retinopathy of prematurity (18.82 ng/ml) than in no retinopathy of prematurity (28.81 ng/ml) ( P = 0.002).

The area under the curve of receiver operating characteristic for both IGF-1 levels and postnatal weight gain was > 0.5, implying good diagnostic accuracy in predicting retinopathy of prematurity.