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New research · Ophthalmology
Indian journal of ophthalmology · 2d
Cohort studyIndian journal of ophthalmology · 2026

Clinical profile and perioperative risk factors for post-cataract surgery nonarteritic anterior ischemic optic neuropathy in an Indian population: An emulated target trial.

Madhumita Gopal, Rohan Arora, Nirmala Devy
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OphthalmologyCohort study

One-fifth of patients with this optic nerve injury had no known risk factors.

Clinical profile and perioperative risk factors for post-cataract surgery nonarteritic anterior ischemic optic neuropathy in an Indian population: An emulated target trial.

Madhumita Gopal … Nirmala Devy
Indian journal of ophthalmology · 2026
Background

Cataract surgery is associated with a four times increased risk of nonarteritic anterior ischemic optic neuropathy (nonarteritic anterior ischemic optic neuropathy).

Purpose

This paper presents the first report of patients from Indian ethnicity with post-cataract surgery nonarteritic anterior ischemic optic neuropathy (psNAION) and aims to evaluate perioperative risk factors for prediction of psNAION.

Methods

A retrospective evaluation of patients who developed psNAION was done and clinical characteristics noted.

Results
21.1%
these patients had no known health risk factors despite developing the condition
More results

Nineteen patients (8 males, 11 females) aged 66.6 ± 7.7 years developed psNAION 80.8 ± 50.6 days after cataract surgery.

Three patients presented <7 days and 16 presented >6 weeks from surgery.

More results

None of the evaluated variables (perioperative blood pressure and blood sugar, and postoperative intraocular pressure) correlated significantly with increased risk of psNAION.

“
Conclusion · 1 of 2

Onset of psNAION is much later in Indian patients. All patients had classical features of nonarteritic anterior ischemic optic neuropathy, and clinical evaluation was sufficient to establish diagnosis.

Conclusion · 2 of 2

One-fifth of patients had no known coexisting risk factors. Perioperative control of blood pressure or blood sugar, and postoperative intraocular pressure were not associated with increased risk.

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