To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on…

StudyOphthalmic epidemiology· Jul 2026

To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on Early-Onset Myopic Control in Western Chinese Children.

Qiwen Chen, Xinyu Peng, Jing Fang … Xinghan Wen

Cataract & RefractiveStudyTreatmentQ1IF 1.9

Adding carteolol eye drops to atropine slowed eye elongation more than atropine alone.

To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on Early-Onset Myopic Control in Western Chinese Children.

Qiwen Chen … Xinghan Wen

Ophthalmic epidemiology · Jul 2026 · Q1 in Ophthalmology

Purpose

To evaluate the inhibitory role of 0.01% atropine combined with 2% carteolol hydrochloride on myopia progression in children aged 3-8 years in western China.

Methods

A total of 78 myopic children (spherical equivalent refraction from -2.00D to -8.00D) were initially assigned based on parental willingness to a control group (artificial tears (Hialid®) once nightly) or a treatment group.

n = 78 myopic children

Results

eyes grew about a tenth of a millimeter longer over 6 months - much less than with atropine alone

Combination

0.09mm

Atropine

0.47mm

Control

0.99mm

More results

Both treatment groups showed significantly reduced SE and axial length progression at 3 and 6 months (all p < 0.001).

IOP decreased in the combination group (-1.75 ± 4.24 mmHg) but increased in the other groups.

Adverse reaction rates were comparable between groups ( p > 0.05).

“

Conclusion

0.01% atropine combined with 2% carteolol hydrochloride safely and effectively inhibits myopia progression in children with early-onset myopia.

To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on Early-Onset Myopic Control in Western Chinese Children.

To Investigate the Effect of Combined Use of 0.01% Atropine and 2% Carteolol Hydrochloride Eye Drops on Early-Onset Myopic Control in Western Chinese Children.

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