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Cohort studyRetina (Philadelphia, Pa.) · 2026

Dropless Pars Plana Vitrectomy Using Intravitreal Decanted Triamcinolone and Moxifloxacin: Safety and Efficacy.

Amr Lotfy Ali, Daniel Vail, Mohamed Sherif Morsy … William R Freeman

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OphthalmologyCohort study

Dropless intravitreal regimen after vitrectomy linked to greater early vision gains than eye drops.

Dropless Pars Plana Vitrectomy Using Intravitreal Decanted Triamcinolone and Moxifloxacin: Safety and Efficacy.

Amr Lotfy Ali … William R Freeman

Retina (Philadelphia, Pa.) · 2026

Purpose

To evaluate the safety and efficacy of a dropless regimen using intravitreal decanted triamcinolone acetonide and moxifloxacin at the conclusion of pars plana vitrectomy (pars plana vitrectomy), compared with standard postoperative topical therapy.

Methods

This retrospective study included consecutive patients undergoing pars plana vitrectomy at a tertiary retina center.

n = 172 eyes

Results

vision improved early on in drop-free group, but worsened slightly with eye drops alone

25ETDRS

Dropless

9.5ETDRS

Topical

More results

The dropless group demonstrated significantly less anterior chamber inflammation at week 2 (P = 0.0008) and at month 3 (P = 0.0223).

Mean central subfield thickness was lower at week 2 (P = 0.001), month 3 (P = 0.0009), and month 6 (P = 0.012).

Cystoid macular edema incidence was reduced (P < 0.001).

More results

IOP was similar between groups, and no endophthalmitis occurred.

“

Conclusion

A dropless intravitreal regimen at the conclusion of pars plana vitrectomy can be a safe and effective alternative to topical therapy, with reduced postoperative inflammation and cystoid macular edema and improved visual outcomes.

Post

Dropless Pars Plana Vitrectomy Using Intravitreal Decanted Triamcinolone and Moxifloxacin: Safety and Efficacy.

Dropless intravitreal regimen after vitrectomy linked to greater early vision gains than eye drops.

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