Contact lens-related versus non-contact lens-related Pseudomonas aeruginosa keratitis: The Midlands…

Cohort studyFrontiers in medicine· 2026

Contact lens-related versus non-contact lens-related Pseudomonas aeruginosa keratitis: The Midlands Infectious Keratitis Study.

Burak Ozturk, Saba Anwar, Khawaja Muhammad Ammar Ali Javed … Darren S J Ting

CorneaCohort studyPrognosisQ1IF 3.4

Contact lens-related Pseudomonas keratitis was associated with much lower odds of poor vision outcome

Contact lens-related versus non-contact lens-related Pseudomonas aeruginosa keratitis: The Midlands Infectious Keratitis Study.

Burak Ozturk … Darren S J Ting

Frontiers in medicine · 2026 · Q1 in General Medicine

Background

Pseudomonas aeruginosa (pseudomonas aeruginosa) is a major cause of infectious keratitis worldwide.

Purpose

This study compared clinical features, risk factors, and outcomes of contact lens-related versus non-contact lens-related pseudomonas aeruginosa keratitis in the United Kingdom (United Kingdom).

Methods

A retrospective cohort study of culture-confirmed pseudomonas aeruginosa keratitis cases that presented to the Birmingham and Midland Eye Centre (Birmingham, United Kingdom) and Queen's Medical Centre (Nottingham, United Kingdom) between August 2016 and January 2020.

n = 66 eyes

Results

contact lens wearers were far less likely to end up with poor vision

OR 0.13 (95% CI 0.01 to 0.84)

CI excludes the null - significant

More results

Contact lens wear accounted for 35 (53.1%) cases.

At presentation, mean CDVA was 1.26 ± 0.96 logMAR (~6/120 Snellen).

Hospitalisation occurred in 71.2% cases, with 19.7% cases requiring surgery.

More results

Compared to non-contact lens-related keratitis, contact lens-related keratitis was more commonly associated with younger age, better initial vision, smaller and non-central ulcers, and absence of hypopyon (all p < 0.05).

“

Conclusion · 1 of 2

Pseudomonas aeruginosa keratitis remains a significant cause of ocular morbidity in the United Kingdom.

Conclusion · 2 of 2

contact lens-related disease shows distinct clinical features and better outcomes likely due to lower presenting disease severity and timely management of the disease.

Contact lens-related versus non-contact lens-related Pseudomonas aeruginosa keratitis: The Midlands Infectious Keratitis Study.

Contact lens-related versus non-contact lens-related Pseudomonas aeruginosa keratitis: The Midlands Infectious Keratitis Study.

Related papers