Outcomes of Therapeutic and Tectonic Penetrating Keratoplasty for Advanced Corneal Disease.

Therapeutic and tectonic penetrating keratoplasty preserved globe integrity in most eyes but were associated with poor graft survival, limited visual recovery, and frequent postoperative complications in this high-risk cohort.

These findings are consistent with presentation at an advanced stage of disease in a tertiary referral setting, as reflected by large graft size and poor baseline visual acuity.