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Randomized trialDiagnostics (Basel, Switzerland) · 2026

Feasibility of Intraoperative SS-OCT for Assessing Capsular-Bag Dynamics During Cataract Surgery: Pilot Randomized Intra-Individual Comparison of Adaptive Versus Gravity-Based Fluidics.

Stefan Georgiev, Stefan Palkovits, Andreea Dana-Fisus … Oliver Findl

OphthalmologyRandomized trial

Intraoperative eye-imaging scans during cataract surgery were only partly successful.

Feasibility of Intraoperative SS-OCT for Assessing Capsular-Bag Dynamics During Cataract Surgery: Pilot Randomized Intra-Individual Comparison of Adaptive Versus Gravity-Based Fluidics.

Stefan Georgiev … Oliver Findl

Diagnostics (Basel, Switzerland) · 2026

Background

This exploratory, randomized, patient-masked, intra-individual pilot study evaluated the feasibility of intraoperative swept-source optical coherence tomography (swept-source optical coherence tomography) for quantifying capsular-bag dynamics during cataract surgery and explored potential differences between an adaptive fluidics system (adaptive fluidics system) and a gravity-based fluidics system (GFS).

Methods

Twenty-seven myopic cataract patients (54 eyes) underwent bilateral phacoemulsification, with one eye randomly assigned to adaptive fluidics system and the fellow eye to GFS using the same phacoemulsification platform (Stellaris/Stellaris Elite, Bausch & Lomb, Rochester, NY, USA).

n = 54 eyes

60.5%

Results

60.5%

of scans yielded usable eye-capsule images, showing feasibility limits

n = 54 eyes

More results

However, this difference was not statistically significant after adjustment for multiple comparisons.

No significant inter-system differences were found at other timepoints, and overall discomfort scores were similar ( p = 0.70).

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Conclusion · 1 of 3

Intraoperative swept-source optical coherence tomography enabled real-time visualization and partial quantitative assessment of capsular-bag dynamics during cataract surgery.

Conclusion · 2 of 3

The observed difference at the initiation of phacoemulsification may suggest reduced anterior-capsule deepening with adaptive fluidics, but this comparison was not statistically significant after multiplicity adjustment.

Conclusion · 3 of 3

The 39.5% measurement failure rate underscores the need for technical refinement before routine clinical implementation.

Post

Feasibility of Intraoperative SS-OCT for Assessing Capsular-Bag Dynamics During Cataract Surgery: Pilot Randomized Intra-Individual Comparison of Adaptive Versus Gravity-Based Fluidics.

Intraoperative eye-imaging scans during cataract surgery were only partly successful.

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