Long-term Infectious Keratitis Microbiology and Resistance Patterns With Forecasts to 2030: A 23-Year Analysis.

Among 4748 cultures, 2918 (61.46%) were positive: bacteria 2624 (89.92%) and fungi 294 (10.08%).

Bacterial isolates were 81.44% Gram+ and 18.56% Gram-.

The leading organisms were Staphylococcus epidermidis, other Gram+, other coagulase-negative staphylococci, Pseudomonas aeruginosa, and Staphylococcus aureus; Fusarium dominated fungi (52.38%).

Gram+ resistance declined in β-lactams/50S agents but increased for fluoroquinolones, vancomycin, and gentamicin.