Retinal and choroidal thickness alterations detected by optical coherence tomography in human immunodeficiency virus patients: A systematic review and meta-analysis.

Standardized mean differences (SMD) were pooled using fixed- or random-effects models.

Peripheral macular ganglion cell layer (SMD 0.17; 95% CI 0.01-0.32;P = 0.034) and outer plexiform layer thickness (SMD 0.35; 95% CI 0.18-0.52;P < 0.001) were significantly increased.

Choroidal thickness was comparable between human immunodeficiency virus-infected individuals and healthy controls (SMD 0.15; 95% CI -0.28-0.58;P = 0.49).