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New research · Ophthalmology
International ophthalmology · 3d
Cohort studyInternational ophthalmology · 2026

Large optical zone transepithelial PRK: refractive and aberration outcomes.

Sultan Kaya Ünsal, Orkun Özkan
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OphthalmologyCohort study

Large-optical-zone transepithelial photorefractive keratectomy achieved excellent refractive accuracy at 6 months.

Large optical zone transepithelial PRK: refractive and aberration outcomes.

Sultan Kaya Ünsal, Orkun Özkan
International ophthalmology · 2026
Purpose

To assess refractive outcomes and corneal higher-order aberration changes following transepithelial photorefractive keratectomy (transepithelial photorefractive keratectomy) performed with large optical zones.

Methods

Data from 222 eyes of 112 myopic patients undergoing single-step transepithelial photorefractive keratectomy with Smart Pulse Technology were reviewed retrospectively.

n = 222 eyes
Results

over 8 in 10 eyes landed very close to their vision target

81.1%
Within ± 0.50 D
98.2%
Within ± 1.00 D
More results

Safety and efficacy were comparable between the LOZ and XLOZ groups, and no clinically significant haze was observed.

Corneal higher-order aberrations increased more in the LOZ group, whereas smaller changes and a slight reduction in coma were observed in the XLOZ group (p < 0.05).

“
Conclusion · 1 of 2

Transepithelial photorefractive keratectomy performed with large optical zones demonstrated excellent refractive predictability, safety, and efficacy.

Conclusion · 2 of 2

The use of extra-large optical zones was associated with smaller increases in corneal higher-order aberrations, suggesting that larger optical zones may help preserve postoperative optical quality after transepithelial photorefractive keratectomy.

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