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Cohort studyJapanese journal of ophthalmology · 2026

Corrected gestational age-specific prediction models for identifying treatment-requiring retinopathy of prematurity.

Sao Sugimoto, Masako Nagahara, Kentaro Hayashi … Taku Toyama

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OphthalmologyCohort study

Retinopathy risk prediction model was most accurate at 34 weeks corrected age

Corrected gestational age-specific prediction models for identifying treatment-requiring retinopathy of prematurity.

Sao Sugimoto … Taku Toyama

Japanese journal of ophthalmology · 2026

Purpose

To develop and validate time-updated, corrected gestational age (corrected gestational age)-specific prediction models for identifying treatment-requiring retinopathy of prematurity (retinopathy of prematurity) using routinely available systemic factors, and to assess longitudinal changes in predictor combinations and model performance with advancing corrected gestational age.

Methods

Retrospective cohort study.

Results

model correctly ranked risk most often when checked at 34 weeks

CGA 28 weeks

0.65AUC

CGA 30 weeks

0.716AUC

CGA 32 weeks

0.809AUC

CGA 34 weeks

0.842AUC

More results

Growth-related and inflammatory indices were repeatedly selected, while overall predictor composition evolved with advancing corrected gestational age.

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Conclusion · 1 of 2

These findings suggest that corrected gestational age-specific prediction models may help characterize the evolving risk of treatment-requiring retinopathy of prematurity.

Conclusion · 2 of 2

However, prospective multicenter validation and further refinement are required before clinical application.

Post

Corrected gestational age-specific prediction models for identifying treatment-requiring retinopathy of prematurity.

Retinopathy risk prediction model was most accurate at 34 weeks corrected age

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