ScholarDeck

Cohort studyBrain sciences · 2026

Herpesvirus-Associated Visual Impairment: Clinical Features, Etiological Spectrum, and Treatment Outcomes in Consecutive Patients from a Tertiary Neurological Clinic.

Lei Liu, Jingxiao Zhang, Qiuying Ma, Jiawei Wang

OphthalmologyCohort study

Varicella zoster virus is the leading cause of herpesvirus-related visual impairment.

Herpesvirus-Associated Visual Impairment: Clinical Features, Etiological Spectrum, and Treatment Outcomes in Consecutive Patients from a Tertiary Neurological Clinic.

Lei Liu … Jiawei Wang

Brain sciences · 2026

Methods

Thirteen consecutive patients (19 affected eyes) with herpesvirus-related visual impairment admitted between January 2016 and January 2025 were enrolled.

n = Thirteen consecutive patients (19

Results

76.9%

vzv caused roughly 3 in 4 herpesvirus-related vision loss cases in this group

n = Thirteen consecutive patients (19

More results

Eight patients (61.5%) developed optic neuritis (optic neuritis) secondary to varicella zoster virus infection, and five patients (38.5%) suffered from acute retinal necrosis (acute retinal necrosis), which was caused by varicella zoster virus ( n = 2), HSV-1 ( n = 2), and pseudorabies virus ( n = 1).

Bilateral involvement occurred in 46.2% (6/13) of patients.

More results

At the disease nadir, 46.2% of patients (6/13) presented with no light perception (no light perception).

All patients received antiviral therapy, 11 of whom (84.6%) were treated with intravenous antiviral agents.

“

Conclusion

Diagnostic delays and insufficient interdisciplinary collaboration contribute substantially to poor outcomes.

Post

Herpesvirus-Associated Visual Impairment: Clinical Features, Etiological Spectrum, and Treatment Outcomes in Consecutive Patients from a Tertiary Neurological Clinic.

Varicella zoster virus is the leading cause of herpesvirus-related visual impairment.

Related papers