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New research · Ophthalmology
Contact lens & anterior eye : the journal of the British Contact Lens Association · 4d
Randomized trialContact lens & anterior eye : the journal of the British Contact Lens Association · 2026

The effect of Intense Pulsed Light therapy on eyelid bacterial load in contact lens discomfort.

Srikanth Dumpati, Fatima Iqbal, Ajay Kumar Vijay … Mark Willcox
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OphthalmologyRandomized trial

Intense pulsed light therapy lowered eyelid bacterial load in contact lens wearers after two sessions

The effect of Intense Pulsed Light therapy on eyelid bacterial load in contact lens discomfort.

Srikanth Dumpati … Mark Willcox
Contact lens & anterior eye : the journal of the British Contact Lens Association · 2026
Purpose

To evaluate the effect of Intense pulsed light (intense pulsed light) therapy on eyelid microbiota in symptomatic contact lens (contact lens) wearers.

Methods

With Contact Lens Dry Eye Questionnaire (CLDEQ-8) score ≥ 12 were enrolled and received two intense pulsed light/sham treatments at three-week intervals.

n = 10
Results

germ counts on the eyelid dropped after intense pulsed light treatment

Day 0
174CFU/sw
Day 42
122CFU/sw
More results

Eighteen contact lens wearers completed the study (intense pulsed light: n = 10; 90% female, aged 35.3 ± 13.2 years; sham: n = 8; 50% female, aged 28.9 ± 6.3 years).

However, by day 90, bacterial count had increased relative to day 42 and was partially rebounded towards baseline numbers.

More results

The sham group showed no significant changes in bacterial load at any follow-up time point.

“
Conclusion · 1 of 2

Intense pulsed light therapy significantly reduced eyelid bacterial load after two treatment sessions in symptomatic contact lens wearers.

Conclusion · 2 of 2

However, this antimicrobial effect diminished by day 90, suggesting that sustained microbiological benefit may require optimized intense pulsed light treatment protocols.

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