Post

New research · Ophthalmology
Pakistan journal of pharmaceutical sciences · 4d
Cohort studyPakistan journal of pharmaceutical sciences · 2026

Effects of levofloxacin eye drops on ocular surface bacterial colonization and postoperative infection rate in patients undergoing blepharoplast.

Shu Wang, Guoping Wu, Wenwen Zhang
Read paper
OphthalmologyCohort study

Levofloxacin eye drops associated with lower postoperative infection rate after blepharoplasty.

Effects of levofloxacin eye drops on ocular surface bacterial colonization and postoperative infection rate in patients undergoing blepharoplast.

Shu Wang … Wenwen Zhang
Pakistan journal of pharmaceutical sciences · 2026
Background

Ocular surface bacterial colonization is a key risk factor for postoperative infection after blepharoplasty, yet clinical evidence on the impact of levofloxacin eye drops remains limited.

Purpose

This study aims to evaluate the actual impact of perioperative levofloxacin eye drops on bacterial colonization density, changes in bacterial spectrum and postoperative infection rates in patients undergoing blepharoplasty.

Methods

This single-center retrospective cohort study reviewed the electronic medical records of 215 patients who underwent blepharoplasty between January 2023 and January 2025.

n = 215 patients
Results

infection risk dropped to nearly 1 in 40 patients with the drops

OR by subgroup · 95% CI
null = 1
protective factor for postoperative
0.23
factor
3.47
More results

Multivariate regression analysis showed that levofloxacin use was a protective factor for postoperative infection (OR = 0.23, 95% CI: 0.07-0.81), while a history of diabetes was an independent risk factor (OR = 3.47, 95% CI: 1.14-10.55).

More results

There was no significant difference in the time to wound healing between the two groups (7.5 ± 1.2 days vs 7.7 ± 1.4 days, p = 0.258).

“
Conclusion

Perioperative levofloxacin eye drops may reduce ocular surface bacterial colonization and the risk of postoperative infection in blepharoplasty patients without delaying wound healing.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
AI / Informatics
0·962 for OCT
MerMED-FM was very accurate at diagnosing diseases using eye scans
AI / Informatics
0.98
Artificial intelligence's eyelid-height measurements matched doctors' manual measurements almost perfectly
AI / Informatics
92.1%
combining eye scans and photos correctly told benign from cancerous lesions apart nearly every time
Cohort Study
28.6%
recurred locally in more than 1 in 4 patients over years of follow-up
Cohort Study
-0.395
excision group's post-op eyelid fullness score was lower - greater improvement
Cohort Study
86.7%
of infants probed after 12 months still had unresolved tear duct blockage
Observational
16%
eyelid tissue in rosacea patients showed less of this key repair-signaling protein inside cell nuclei
Cohort Study
25%
about 1 in 4 treated cases had symptoms return after improving