Post

New research · Ophthalmology
American journal of ophthalmology · 4d
Case-controlAmerican journal of ophthalmology · 2026

Non-infectious Uveitis is Associated With Increased Psychiatric Comorbidities: An All of Us research program Analysis.

Priya Marella, Vijay Subramanian, Miriam Habiel
Read paper
OphthalmologyCase-control

Non-infectious uveitis is linked to much higher odds of mood disorders.

Non-infectious Uveitis is Associated With Increased Psychiatric Comorbidities: An All of Us research program Analysis.

Priya Marella … Miriam Habiel
American journal of ophthalmology · 2026
Purpose

This study aims to evaluate the psychiatric comorbidities of non-infectious uveitis (non-infectious uveitis) and screening tool usage through a matched case-control approach.

Methods

Retrospective cross-sectional study.

n = 3,266
Results

eye inflammation patients had much higher odds of also having a mood disorder

OR 3.31 (95% CI 3.08 to 3.56)
null 1
3.08
3.56
CI excludes the null - significant
More results

The association between non-infectious uveitis and depression, anxiety, substance and opioid abuse was stronger in Black participants than White participants.

The frequency of PHQ-2 and PHQ-9 questionnaire usage was low among non-infectious uveitis patients with a total of 4.8% and 1.4% respectively.

“
Conclusion · 1 of 2

Non-infectious uveitis is strongly associated with psychiatric comorbidities, particularly in Black patients.

Conclusion · 2 of 2

Ophthalmologic examination and the use of screening tools for psychiatric comorbidities can provide early observation of symptoms and is recommended in non-infectious uveitis patients.

Read paper
0 comments

No comments yet. Be the first.

Related papers

LatestFoundational
AI / Informatics
0·962 for OCT
MerMED-FM was very accurate at diagnosing diseases using eye scans
AI / Informatics
0.98
Artificial intelligence's eyelid-height measurements matched doctors' manual measurements almost perfectly
AI / Informatics
92.1%
combining eye scans and photos correctly told benign from cancerous lesions apart nearly every time
Cohort Study
28.6%
recurred locally in more than 1 in 4 patients over years of follow-up
Cohort Study
-0.395
excision group's post-op eyelid fullness score was lower - greater improvement
Cohort Study
86.7%
of infants probed after 12 months still had unresolved tear duct blockage
Observational
16%
eyelid tissue in rosacea patients showed less of this key repair-signaling protein inside cell nuclei
Cohort Study
25%
about 1 in 4 treated cases had symptoms return after improving